Vitamin D Status at Birth and Future Risk of Attention Deficit/Hyperactivity Disorder (ADHD)
نویسندگان
چکیده
OBJECTIVE To investigate whether children with Attention Deficit/Hyperactivity Disorder have lower levels of Vitamin D3 at birth than matched controls. MATERIAL Umbilical cord blood samples collected at birth from 202 children later diagnosed with Attention Deficit/Hyperactivity Disorder were analysed for vitamin D content and compared with 202 matched controls. 25-OH vitamin D3 was analysed by liquid chromatography tandem mass spectrometry. RESULTS No differences in cord blood vitamin D concentration were found between children with Attention Deficit/Hyperactivity Disorder (median 13.0 ng/ml) and controls (median 13.5 ng/ml) (p = 0.43). In a logistic regression analysis, Attention Deficit/Hyperactivity Disorder showed a significant association with maternal age (odds ratio: 0.96, 95% confidence interval: 0.92-0.99) but not with vitamin D levels (odds ratio: 0.99, 95% confidence interval: 0.97-1.02). CONCLUSION We found no difference in intrauterine vitamin D levels between children later developing Attention Deficit/Hyperactivity Disorder and matched control children. However, the statistical power of the study was too weak to detect an eventual small to medium size association between vitamin D levels and Attention Deficit/Hyperactivity Disorder.
منابع مشابه
Vitamin D Status and Its Association with Attention Deficit Hyperactivity Disorder (ADHD) in Children
متن کامل
بررسی رابطه اختلال نقص توجه/بیش فعالی و نارسی در اطفال سنین 13 - 7 سال مراجعه کننده به مراکز بهداشتی شهرستان رفسنجان در سال 1392
Background & Aims: Attention deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children. Lack of attention and recognition can have harmful effects on the individual and family. This study aimed to investigate the relationship between attention deficit / hyperactivity (ADHD) in children with premature birth. Materials & Methods: In this cross-secti...
متن کاملEvaluation of the Relative Frequency of Attention Deficit Hyperactivity Disorder (ADHD) in 6-Year-Old Children with Low Birth Weight in Yazd
Introduction: ADHD (attention deficit hyperactivity disorder) is a neuro-behavioral syndrome that is characterized by a lack of attention, irritability, high activity, distressed behaviors, especially in boys. Materials and Methods: A cohort study was conducted on 120 children aged 6 years. 60 children with low birth weight (less than 2500 g) as exposed group and 60 children with birth weight m...
متن کاملPrevalence of Attention Deficit Hyperactivity Disorder in Adults Hospitalized in Toxicology Ward of Mashhad University of Medical Sciences with Alcohol Poisoning
Background: Attention Deficit Hyperactivity Disorder (ADHD) is a common psychiatric disorder among children and adolescents that can be continued into adulthood in 30 to 50% of cases. Adult ADHD disorder can affect the performance of an individual and may predispose to drug abuse, alcoholism, smoking, sexual offenses, violation of law, educational and other social problems. The coincidences of ...
متن کامل